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Vioxx is a nonsteroidal anti-inflammatory drug (NSAID) known as a COX-2 inhibitor used to relieve the symptoms of osteoarthritis and to treat pain and menstrual discomfort.

Before using
Some medicines or medical conditions may interact with this medicine. Inform your doctor or pharmacist of all prescription and over-the-counter medicine that you are taking. Additional monitoring of your dose or condition may be needed if you are taking an ace inhibitor, anticoagulant, furosemide, lithium, methotrexate, rifampin, thiazide diuretics, or warfarin. Inform your doctor of any other medical conditions including aspirin-sensitive asthma, allergies, pregnancy, or breast-feeding. Contact your doctor or pharmacist if you have any questions or concerns about Vioxx.

The usual dose of Vioxx for acute pain syndromes and menstrual cramps (primary dysmenorrhea) is 50 mg once daily for no longer than 5 days. The usual dose of Vioxx for treatment of osteoarthritis is 12.5 mg daily although some patients may benefit from 25 mg daily. The maximum daily dose should not exceed 25 mg. This medicine may be taken on an empty stomach or with food.

STORE THIS MEDICINE at room temperature at 70 to 77 degrees F (25 degrees C) in a tightly-closed container, away from heat, moisture, and light.

Miss a dose
If you miss a dose of this medicine, and you are taking 1 dose daily, take the missed dose if you remember the same day. Skip the missed dose if you do not remember until the next day. DO NOT take 2 doses at once.

Do not take this medicine if you have had severe allergic reaction to aspirin or any medicine containing aspirin or to a nonsteroidal anti-inflammatory drug (such as Feldene, Motrin, Naprosyn, Clinoril). A severe reaction includes a severe rash, hives, breathing difficulties, or dizziness. If you have a question about whether you are allergic to Vioxx or if a certain medicine is a nonsteroidal anti-inflammatory drug, contact your doctor or pharmacist. If you experience difficulty breathing; tightness of chest; swelling of eyelids, face, or lips; or if you develop a rash or hives, tell your doctor immediately. Do not take any more doses of this medicine unless your doctor tells you to do so. DO NOT exceed the recommended dose or take this medicine for longer than prescribed without checking with your doctor. Keep ALL doctor and laboratory appointments while you are using this medicine.

Alcohol warning
If you consume 3 or more alcoholic drinks every day, ask your doctor whether you should take this medicine or other pain relievers/fever reducers. This medicine may cause stomach bleeding.

Before a new medicine
Before you begin taking any new medicine, either prescription or over-the-counter, check with your doctor or pharmacist. This includes any medicines that contain ibuprofen, naproxen, or ketoprofen.

For women
If you plan on becoming pregnant, discuss with your doctor the benefits and risks of using this medicine during pregnancy. It is unknown if this medicine is excreted in breast milk. DO NOT breast feed while taking this medicine.

Side effects
Side effects that may occur while taking this medicine include weakness or nausea. If they continue or are bothersome, check with your doctor.

Call your doctor
Check in with your doctor immediately if you experience itching or skin rash, swelling of the feet or ankles, unexpected weight gain, vomiting material that looks like coffee grounds, or blood in stool or vomit.

Contact your doctor
Contact your doctor immediately if you experience swelling of hands, face, lips, eyes, throat, or tongue; difficulty swallowing or breathing; hoarseness; flu-like symptoms; sluggishness; yellowing of the skin or eyes; stomach pain; dark urine or pale stools; or unusual fatigue. If you notice other effects not listed above, contact your doctor, nurse, or pharmacist.

DO NOT share this medicine with others for whom it was not prescribed. DO NOT use this medicine for other health conditions. Keep this product out of the reach of children. If using this medicine for an extended period of time, obtain refills before your supply runs out.

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Vioxx Prescription

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Vioxx Description
ROFECOXIB - ORAL (row-feh-COX-ib)

Common Vioxx Brand Name(s)

Vioxx Side Effects
Stomach upset or tiredness may occur. If these effects persist or worsen, notify your doctor promptly. Unlikely but report promptly black or bloody stools, stomach pain, severe headache or a change in the amount of urine. Very unlikely but report promptly dark urine or yellowing eyes or skin. In the unlikely event you have an allergic reaction to this drug, seek immediate medical attention. Symptoms of an allergic reaction include rash, itching, swelling, dizziness or trouble breathing. If you notice other effects not listed above, contact your doctor or pharmacist.

How To Use Vioxx
VIOXX: Take VIOXX by mouth, generally once daily as directed. To decrease the chance of stomach upset, VIOXX is best taken with food. Dosage is based on your medical condition and response to therapy. Take VIOXX with 6 to 8 ounces (180-240ml) of water. Do not lie down for at least 30 minutes after taking VIOXX.

Vioxx Uses
VIOXX is a nonsteroidal anti-inflammatory drug (NSAID) which relieves pain and swelling (inflammation). It is used to treat arthritis, menstrual pain or other acute pain.

Vioxx Precautions
Tell your doctor your medical history, including any allergies (especially to aspirin/other NSAIDs); liver, kidney, or heart disease; stomach/intestinal ulcers or bleeding; history of smoking, alcoholism, asthma, high blood pressure; growths in the nose (e.g., nasal polyps); serious infections, swelling (edema), blood disorders (anemia) or poorly controlled diabetes. This medicine may cause stomach bleeding. Daily use of alcohol, especially when combined with this medicine, may increase your risk for stomach bleeding. Check with your doctor or pharmacist for more information. Caution is advised when VIOXX is used in the elderly, as this group may be more sensitive to drug side effects. VIOXX should be used only when clearly needed during the first six months of pregnancy. It should not be used during the last three months of pregnancy. Discuss the risks and benefits with your doctor. It is not known whether VIOXX is excreted into breast milk. Because of the potential risk to the infant, breast-feeding while using VIOXX is not recommended. Consult your doctor before breast-feeding.

Vioxx Drug Interactions
Tell your doctor of all prescription and nonprescription medication you may use, especially medicines for high blood pressure (e.g., ACE Inhibitors such as lisinopril); "water pills" (diuretics such as furosemide or thiazides); other NSAIDs or aspirin (e.g., ibuprofen); lithium, methotrexate; corticosteroids (e.g., prednisone); rifamycins (e.g., rifampin) or "blood thinners" (e.g., warfarin). Check all nonprescription medicine labels carefully, since many contain pain relievers/fever reducers (NSAIDs/aspirin) which are similar to VIOXX. Aspirin as prescribed by your doctor for reasons such as heart attack or stroke prevention (i.e., non- arthritis doses) should be continued. Consult your pharmacist. Do not start or stop any medicine without doctor or pharmacist approval.

Vioxx Overdose
If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include severe stomach pain, coffee ground-like vomit, dark stool, ringing in the ears, change in amount of urine, unusually fast or slow heartbeat, muscle weakness, slow or shallow breathing, confusion, severe headache or loss of consciousness.

Vioxx Notes
Do not share VIOXX with others. Laboratory or medical tests may be performed to monitor your progress.

Missed Vioxx Dose
If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

Vioxx Storage
Store at room temperature (77 degrees F or 25 degrees C) away from light and moisture.


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